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Description

GP000105: MUC1(126-149)-STn(139,140)C133H209N33O58 3198. 27 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Pro126 Gly149; UniProt position 126 149, aa length 24) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Sialyl Tn or STn (Neu5Ac2 6GalNAc O Ser) at Ser140 and Neu5Ac2 6GalNAc O Thr at Thr139. The C terminus is carboxylic acid. MUC1(126 149) STn(139,140) Mucin1; Synthetic MUC 1 (di STn) glycopeptide

87 / An Fmoc-protected L-serine building block carrying a β-D-lactose (Galβ1-4Glc) disaccharide

Fmoc-L-Ser((Ac)3-Fuc-α-L)-OH

Benzyl Ester

The installed glycan is a lactose (Galβ1-4Glc) disaccharide

09 / A Blood Group A trisaccharide (GalNAcα1-3[Fucα1-2]Gal) ligand equipped with a biotin tag

STn Antigen (Serine)

C62H98N16O28 / 1515

22 / An α-L-rhamnose ligand equipped with an amine-functionalized linker through a short ethyl spacer

C63H79N3O32 / 1390

28 / / Ciprofibrate Acyl-O-β-D Glucuronide / Ciprofibrate Glucuronide

blocked amino acid)

41 / A β-D-lactose ligand equipped with a terminal carboxylic acid through a short butyl spacer